Antibacterial greener silver nanoparticles synthesized using Marsilea quadrifolia extract and their eco-friendly evaluation against Zika virus vector, Aedes aegypti

Abstract

Fabrication and use of nanoparticles have progressively enlarged within the last decade. Herein the silver nanoparticles (AgNps) were synthesized via the extract from Marsilea quadrifolia (Mq) as a decreasing and steadying mediator. The Mq-AgNPs demonstrated superior toxicity on Zika virus vector, Aedes aegypti with the LC50 value of 10.69 μg·mL-1. The Mq-AgNPs were established securely to non-target organisms Artemia nauplii and Ceriodaphnia cornuta, and no structural or anatomical alterations confirm its security to the surroundings. The antibacterial activity exposed that Mq-AgNPs showed superior growth inhibition effect against the tested bacteria. Furthermore, the Mq-AgNPs showed strong antioxidant activities when compared to Mq leaf extract. Overall, our results highlight that Mq-AgNPs are hopeful and biodegradable devices against mosquito vectors of therapeutic significance, with moderate toxicity against non-target aquatic animals.