Inhibition of lysozyme fibrillation by functional groups in graphene oxide quantum dots

Abstract

Graphene oxide quantum dots (GOQDs) were enriched with carboxyl and hydroxyl groups, respectively, to characterize their effect on modulating the assembly of lysozyme. The hydroxyl enriched GOQDs showed the strongest inhibition effect for the fibrillation of lysozyme, which may due to the enhanced electrostatic interactions to proteins.