Eukaryotic promoters?

Abstract

Eukaryotic promoters are much more complex and diverse than prokaryotic promoters. Eukaryotic promoters span a wide range of DNA sequences. It is not unusual to have several regulatory elements such as enhancers several kilobases away from the TSS. Eukaryotic promoters are so complex in structure that the DNA tends to fold back on itself which helps to explain how many physically distant DNA sequences can affect transcription of a given gene. The TATA-binding protein binds the TATA box and helps in the subsequent binding of the RNA polymerase. A transcription complex is constructed from the RNA polymerase and several transcription factor proteins.