Antibacterial and Phytochemical Analysis of Ethanolic Extract of Ananas comosus (Pineapple) Peel

Abstract

The rapidly increasing global population and the impending food shortages in near future necessitate sustainable strategies to meet the prospective nutritional requirements in addition to basic food needs. Concerning this, one promising approach is the use of fruit peels as nutraceutical which may provide health benefits. Ananas comosus (pineapple) peel are abundant in bioactive compounds, particularly polyphenols, which offer potential therapeutic effects and boosts overall health. The present study was carried out to assess the total polyphenol content, phytochemical profile, and antibacterial potential of the ethanolic extract of pineapple peel (PPEE). The phytochemical composition of PPEE was identified using HRLCMS-QTOF in both positive and negative ionization modes, it showed the presence of variety of phenolic and polyphenolic compounds, the total polyphenol content was 359.14 ± 2.12 mg GAE/g. The antibacterial activity of PPEE was evaluated against six organisms including Escherichia coli NCIM 2065, Proteus vulgaris NCIM 2027, Shigella flexneri NCIM 5265, Staphylococcus aureus NCIM 2079, Pseudomonas aeruginosa NCIM 2036 and Lactobacillus casei var shirota. using agar well diffusion method. PPEE inhibited all the test pathogens at 50 mg/mL concentration while had no inhibitory effect on L. casei var shirota.