Inhibitory Effect of Mentha Piperita Extracts against Herpes Simplex Virus Isolated from Eye Infection

Abstract

Herpes simplex virus (HSV) is one of the common pathogenic viruses of humans bing. This study aimed to determin anti-herpes virus activity of Mentha Piperita extracts in vitro. Mentha Piperita extracts can inhibit HSV infection when the cells treated before viral adsorbtion. HSV-1 were also inhibited by menthol after viral adsorption. HSV-1 viral particles were directly inhibited and viral yield was reduced when treated with Mentha Piperita extracts and menthol. Therefore, Mentha Piperita extracts and menthol showed anti-HSV activities at various stages of the viral replication cycle.