Abstract
New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition while serving as leads for designing future new drugs. This annual review describes the most likely process-scale synthetic approaches to 29 new chemical entities (NCEs) that were approved for the first time in 2015.
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CITATION STYLE
Flick, A. C., Ding, H. X., Leverett, C. A., Kyne, R. E., Liu, K. K. C., Fink, S. J., & O’Donnell, C. J. (2017, August 10). Synthetic Approaches to the New Drugs Approved during 2015. Journal of Medicinal Chemistry. American Chemical Society. https://doi.org/10.1021/acs.jmedchem.7b00010
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