Introduction to Biochemical Toxicology

Abstract

3rd ed. 1. Biochemical toxicology: definition and scope / Ernest Hodgson and Robert C. Smart -- 2. Overview of molecular techniques in toxicology: genes/transgenes / Robert C. Smart -- 3. Immunochemical techniques in toxicology / Gerald A. LeBlanc -- 4. Overview of cellular techniques in toxicology / Sharon A. Meyer -- 5. Metabolism of toxicants: phase I reactions and pharmacogenetics / Ernest Hodgson and Joyce A. Goldstein -- 6. Conjugation and elimination of toxicants / Gerald A. LeBlanc and Walter C. Dauterman -- 7. Physiological factors affecting xenobiotic metabolism / Martin J.J. Ronis and Helen C. Cunny -- 8. Adaptation to toxicants / Randy L. Rose and Ernest Hodgson -- 9. Reactive metabolites and toxicity / Patricia E. Levi and Ernest Hodgson -- 10. Mechanisms of chemically induced cell injury and cellular protection mechanisms / Donald J. Reed. 11. Nutritional factors / William E. Donaldson -- 12. Toxicant-receptor interactions: fundamental principles / Richard B. Mailman and Cindy P. Lawler -- 13. Effects of toxicants on electron transport and oxidative phosphorylation / Donald E. Moreland -- 14. Effects of toxicants on nucleic acid and protein metabolism / David J. Holbrook -- 15. Carcinogenesis / Robert C. Smart and Jacqueline K. Akunda -- 16. Genetic toxicology / R. Julian Preston -- 17. Molecular epidemiology / Mariana C. Stern, P.E. Norbert, P. Koper, and Jack A. Taylor -- 18. Biochemical toxicology of the pheripheral nervous system / Pierre Morell, Jeffry F. Goodrum, and Thomas W. Bouldin -- 19. Biochemical toxicology of the central nervous system / Bonnie L. Blake, Cindy Pl Lawler, and Richard B. Mailman. 20. Hepatotoxicity / Sharon A. Meyer and Arun P. Kulkarni -- 21. Dermatotoxicology / Nancy A. Monteiro-Riviere -- 22. Reproductive and developmental toxicity / Stacy Branch -- 23. Immunotoxicity / MaryJane K. Selgrade, Dori R. Germolec, Robert W. Luebke, Ralph J. Smialowicz, Marsha D. Ward, and Denise M. Sailstad -- 24. Respiratory tract toxicity / Rogene F. Henderson and Kristen J. Nikula -- 25. Biochemical mechanisms of renal toxicity / Joan B. Tarloff -- 26. Cardiovascular toxicity / Alan B. Combs, Kenneth Ramos, and Daniel Acosta.