Fractal geometry of nature (bone) may inspire medical devices shape

Abstract

Medical devices, as orthopaedics prostheses and dental implants, have been designed over years on the strength of mechanical, clinical and biological indications. This sequence is the commonly accepted cognitive and research process: adapting the device to the surrounding environment (host tissue). Inverting this traditional logical approach, we started from bone microarchitecture analysis. Here we show that a unique geometric rule seems to underlie different morphologic and functional aspects of human jaw bone tissue: fractal properties of white trabeculae in low quality bone are similar to fractal properties of black spaces in high quality bone and vice versa. These data inspired the fractal bone quality classification and they were the starting point for reverse engineering to design specific dental implants threads. We introduce a new philosophy: bone decoding and with these data devices encoding. In the future, the method will be implemented for the analysis of other human or animal tissues in order to project medical devices and biomaterials with a microarchitecture driven by nature.