Journal ArticleOPEN ACCESS

Colonic mucosal proliferation is related to serum deoxycholic acid levels

  • Ochsenk�hn T
  • Bayerd�rffer E
  • Meining A
  • et al.
Cancer (1999) 85(8) 1664-1669
DOI: 10.1002/(sici)1097-0142(19990415)85:8<1664::aid-cncr4>3.0.co;2-o
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Abstract

Hyperproliferation of the colorectal mucosa is regarded as an early step in colorectal carcinogenesis. Deoxycholic acid, a secondary bile acid, stimulates colorectal epithelial proliferation in animals and is considered a tumor promoter in human colorectal carcinogenesis. The aim of this study was to investigate the correlation between colorectal mucosal proliferation and the serum deoxycholic acid level.

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APA

Ochsenk�hn, T., Bayerd�rffer, E., Meining, A., Schinkel, M., Thiede, C., N�ssler, V., … Paumgartner, G. (1999). Colonic mucosal proliferation is related to serum deoxycholic acid levels. Cancer, 85(8), 1664–1669. https://doi.org/10.1002/(sici)1097-0142(19990415)85:8<1664::aid-cncr4>3.0.co;2-o

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