A triazine dye, cibacron blue F3GA, decreases oxacillin resistance in methicillin-resistant Staphylococcus aureus

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Abstract

Cibacron blue F3GA (CB) was found to reduce the MIC of oxacillin for methicillin-resistant Staphylococcus aureus (MRSA). This effect was not observed with methicillin-susceptible S. aureus. CB alters the resistance level of MRSA through a factor(s) other than mecA-related products, major autolysins, or femAB products. The exact target(s) of CB in causing the effect is unknown.

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Shirai, C., Sugai, M., Komatsuzawa, H., Ohta, K., Yamakido, M., & Suginaka, H. (1998). A triazine dye, cibacron blue F3GA, decreases oxacillin resistance in methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 42(5), 1278–1280. https://doi.org/10.1128/aac.42.5.1278

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