Selective mitochondrial accumulation of cytotoxic dinuclear polypyridyl ruthenium(II) complexes

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Abstract

The lipophilic ligand-bridged dinuclear cation Rubb16 is significantly cytotoxic and preferentially accumulates in the mitochondria of the L1210 murine leukemia cancer cell line. © 2010 The Royal Society of Chemistry.

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Pisani, M. J., Weber, D. K., Heimann, K., Collins, J. G., & Keene, F. R. (2010). Selective mitochondrial accumulation of cytotoxic dinuclear polypyridyl ruthenium(II) complexes. Metallomics, 2(6), 393–396. https://doi.org/10.1039/c004922k

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