Palladates of the [NHC⋅H][Pd(NH2)(CC)Cl2] Type as Effective Pre-catalysts for the Formation of C−C and C−N Bonds

Abstract

The environmentally friendly, simple synthesis of a family complexes of the general formula [NHC⋅H][Pd(NH2)(CC)Cl2] (CC=biphenyl) is presented. The catalytic activity of these air- and moisture-stable complexes was evaluated as a function of the imidazolium counterion. These pre-catalysts can be converted, under catalytic conditions, to Pd-NHC species enabling the Suzuki–Miyaura, Sonogashira, and Buchwald–Hartwig amination reactions under very mild operating conditions.