How an Increased Intake of Alpha-Tocopherol Can Suppress the Bioavailability of Gamma-Tocopherol

Abstract

George Wolf, DPhil-Tocopherol is the only form of vitamin E in vitamin supplements, whereas-tocopherol is the predominant form of vitamin E in the US diet.-Tocopherol has beneficial properties as an anti-inflammatory and possibly anti-atherogenic and anticancer agent. Excess -tocopherol taken in supplements causes a reduction of-tocopherol concentration in plasma. The biochemical mechanism of this effect, which is important to human nutrition, has recently been elucidated.