Asymmetric Synthesis and Reactions of cis-N-(p-Toluenesulfinyl)aziridine-2-carboxylic Acids

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Abstract

Cis-Aziridine-2-carboxylic acids, 2, precursors of the difficult to prepare syn-β-hydroxy-α-amino acid structural unit, are prepared in high diastereomeric purity by a Darzens-type reaction of the lithium enolate of methyl bromoacetate with enantiopure sulfinimines 1. © 1994, American Chemical Society. All rights reserved.

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Davis, F. A., Zhou, P., & Reddy, G. V. (1994, June 1). Asymmetric Synthesis and Reactions of cis-N-(p-Toluenesulfinyl)aziridine-2-carboxylic Acids. Journal of Organic Chemistry. https://doi.org/10.1021/jo00091a001

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