Abstract
We investigated whether smoking is associated with mutations in the Von Hippel-Lindau (VHL) gene in 337 cases of sporadic renal cell carcinoma (RCC) among 120 852 people followed for 11.3 years; the findings suggest that smoking causes RCC independently of VHL gene mutations. © 2006 Cancer Research.
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Van Dijk, B. A. C., Schouten, L. J., Oosterwijk, E., Hulsbergen-Van De Kaa, C. A., Kiemeney, L. A. L. M., Goldbohm, R. A., … Van Den Brandt, P. A. (2006). Cigarette smoking, von Hippel-Lindau gene mutations and sporadic renal cell carcinoma. British Journal of Cancer, 95(3), 374–377. https://doi.org/10.1038/sj.bjc.6603281
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