Abstract
UVA has long been known for generating an oxidative stress in cells. In this paper we review the different types of DNA damage induced by UVA, i.e. strand breaks, bipyrimidine photoproducts, and oxidatively damaged bases. Emphasis is given to the mechanism of formation that is further illustrated by the presentation of new in vitro data. Examples of oxidation of proteins involved in DNA metabolism are also given. © 2011 IOP Publishing Ltd.
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CITATION STYLE
Girard, P. M., Francesconi, S., Pozzebon, M., Graindorge, D., Rochette, P., Drouin, R., & Sage, E. (2011). UVA-induced damage to DNA and proteins: Direct versus indirect photochemical processes. In Journal of Physics: Conference Series (Vol. 261). Institute of Physics Publishing. https://doi.org/10.1088/1742-6596/261/1/012002
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