Therapy-related myeloid neoplasms after autologous hematopoietic stem cell transplantation in lymphoma patients

Abstract

AML, acute myeloid leukemia; ASCT, autologous hematopoietic stem cell transplantation; t-MN, therapy-related myeloid neoplasm; PBPC, peripheral blood progenitor cells; TBI, total body irradiation; XRCC1, X-ray repair cross-complementing 1; FISH, fluorescent in-situ hybridization, GVHD, graft-versus-host-disease; MDS, myelodysplastic syndrome; MTHFR, methylenetetrahydrofolate reductase, GSTM1, glutathione S-transferase mu 1; PTPRT, protein tyrosine phosphatase, receptor type; P72R, proline 72 arginine; BEAM, BCNU, etoposide, Ara-C and melphalan; NHL, non-Hodgkin lymphoma; MOPP, mechlorethamine, chlorambucil, cyclophosphamide, and lomustine; HL, Hodgkin lymphoma; NA, not available. © 2013 Landes Bioscience.