We describe RosettaRemodel, a generalized framework for flexible protein design that provides a versatile and convenient interface to the Rosetta modeling suite. RosettaRemodel employs a unified interface, called a blueprint, which allows detailed control over many aspects of flexible backbone protein design calculations. RosettaRemodel allows the construction and elaboration of customized protocols for a wide range of design problems ranging from loop insertion and deletion, disulfide engineering, domain assembly, loop remodeling, motif grafting, symmetrical units, to de novo structure modeling. © 2011 Huang et al.
CITATION STYLE
Huang, P. S., Ban, Y. E. A., Richter, F., Andre, I., Vernon, R., Schief, W. R., & Baker, D. (2011). Rosettaremodel: A generalized framework for flexible backbone protein design. PLoS ONE, 6(8). https://doi.org/10.1371/journal.pone.0024109
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