ACTIVITY TEST OF ETHANOL EXTRACT OF JERINGAU RHIZOME (Acorus Calamus L.) AS ANTIBACTERIAL AGAINST of Staphylococcus aureus AND Escherichia coli

  • Misrahanum M
  • Fitri R
  • Ismail Y
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Abstract

Jeringau rhizome (Acorus calamus L.) have the potency to be an antibacterial. This research aimed to find the activity of the ethanol extract of jeringau rhizome on the growth of Staphylococcus aureus and Escherichia coli bacteria. This research utilized an experimental method of maceration with ethanol solvent, phytochemical screening, and activity testing with concentrations of 2,5; 5; 10; 15, and 20% using a well diffusion method. The phytochemical screening shows that the extract contains compounds of alkaloids, tannins, flavonoids, saponins, and triterpenoids. The activity test has shown that the jeringau rhizome extract could obstruct the growth of bacteria from the lowest concentration of 2,5% on 6,86 mm of S. aureus and 7,36 mm on E. coli. The largest restrictive zone was at 20% concentration with a 10,73 mm diameter of S. aureus and 12,63 mm of E. coli.

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Misrahanum, M., Fitri, R., & Ismail, Y. S. (2022). ACTIVITY TEST OF ETHANOL EXTRACT OF JERINGAU RHIZOME (Acorus Calamus L.) AS ANTIBACTERIAL AGAINST of Staphylococcus aureus AND Escherichia coli. Journal of Pharmaceutical And Sciences, 5(2), 294–300. https://doi.org/10.36490/journal-jps.com.v5i2.134

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