Green Synthesis of Gold Nanoparticles and Their Cytotoxic Effect in Breast Cancer: An Experimental and Theoretical Study

Abstract

In this work, the synthesis of gold nanoparticles was studied using an electrolyte generated from a bisphthalimide. Both the nanoparticles and the electrolyte were tested to determine their cytotoxic effects on breast cancer cells of the MCF-7 and MDA-MB-231 lines. For this purpose, 6000 cells were seeded per well in a 96-well plate, and the XTT colorimetric assay was used. Additionally, AutoDock and GOLD were used to determine the structure-structure interactions during molecular docking.