An alkaloid of dioscorea hispida, Dennst

Abstract

THE alkaloid dioscorine, C13H19O2N, was first isolated in 1894 by Boorsma1 from Dioscorea hirsuta, Bl., and obtained in a crystalline condition by Schutte2. On the basis of degradation experiments, Gorter3 in 1911 suggested that the alkaloid belonged to the tropane group, and proposed the following structure: © 1951 Nature Publishing Group.