The role of hollow magnetic nanoparticles in drug delivery

Abstract

The increasing number of scientific publications focusing on nanomaterials in the biomedical field indicates growing interest from the broader scientific community. Nanomedicine is a modern science, and research continues into the application of nanoscale materials for the therapy and diagnosis of damaged tissues. In this regard, substantial progress has been made in the synthesis of magnetic materials with desired sizes, morphologies, chemical compositions, and surface chemistry. Among these, magnetic iron oxide nanoparticles have demonstrated great promise as unique carriers in the delivery of chemical drugs due to their combinations of hollow structures. Importantly, due to the combination of the ability to respond to an external magnetic field and the rich possibilities of their coatings, magnetic materials are universal tools for the magnetic separation of small molecules, biomolecules, and cells. This review provides an overview of the synthesis and biological applications of hollow magnetic nanoparticles in drug delivery systems.