Endurance training minimizes age-related changes of left ventricular twist-untwist mechanics

Abstract

Background The aim of this study was to test the effect of endurance training on the age-related changes of left ventricular (LV) twist-untwist mechanics. Aging has been shown to induce a decline of diastolic function and more recently an impairment of twist-untwist mechanics, which constitutes an important factor for early diastolic suction and filling. On the other hand, endurance training has been shown to improve cardiac function. Methods Speckle-tracking echocardiography was performed in 106 endurance-trained male athletes and 75 controls (age range 18-70 years), divided into three groups according to age. Results From the younger to older age groups, progressive increases in LV apical rotation and twist angle and a decrease in LV untwisting rate during isovolumic relaxation time were observed. Athletes had lower systolic twist angles (P