Abstract
The first in vivo hyperpolarized 129Xe NMR study in experimental tumors is presented. Hyperpolarized 129Xe was dissolved in solutions, and was injected intratumorally in GH-3 prolactinomas in rats and RIF-1 fibrosarcomas in mice. The 129Xe NMR spectra and apparent spin-lattice relaxation times in the two tumor types present characteristic differences. These differences are discussed in terms of xenon exchange between the carrier medium and the tissue compartments. © 2001 Wiley-Liss, Inc.
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Wolber, J., McIntyre, D. J. O., Rodrigues, L. M., Carnochan, P., Griffiths, J. R., Leach, M. O., & Bifone, A. (2001). In vivo hyperpolarized 129Xe NMR spectroscopy in tumors. Magnetic Resonance in Medicine, 46(3), 586–591. https://doi.org/10.1002/mrm.1231
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