Polyarthritis in adults with hypogammaglobulinaemia and its rapid response to immunoglobulin treatment

Abstract

Five patients with primary hypogammaglobulinaemia developed a severe polyarthritis that had some features in common with rheumatoid arthritis. Their joint disease could be distinguished from rheumatoid arthritis, however, by the dramatic improvement after gamma-globulin treatment. The arthritis of hypogammaglobu- linaemia can, therefore, be included among the few potentially curable polyarthritides. © 1976, British Medical Journal Publishing Group. All rights reserved.