Application of kinetic plots in gas and liquid chromatography for the optimization of separation conditions

Abstract

This review describes the recent achievements and historical background of investigations in optimization procedures in gas and liquid chromatographic techniques. The optimization parameters are varied depending on researcher interests and may include separation efficiency, analysis time, column operation pressure, packing characteristics, etc. As it is shown the kinetic performance limit is one of the most used and vital concepts for gas and liquid chromatography. Application of the concept sometimes requires additional cumbersome calculations but nevertheless it provides the most grounded comparison of different packings, columns, and techniques.