Free radical scavenging activity of selected sea cucumber species from Mataram-Lombok, Indonesia

Abstract

Sea cucumber is an important food and remedies in Eastern hemisphere. However, less study have been performed to identify health benefit effects of sea cucumber from tropical region. In this study, radical scavenging activity of sea cucumber from Mataram - Lombok [Holothuria leucospilota, Holothuria atra, Holothuria fuscocinerea, and Holothuria excellens] were studied. Compared to other species at concentration of 0.1 mg mL–1, H. atra extract showed strongest scavenging activity in 2,2-Diphenyl-1-picrylhydrazyl (DPPH) (13.14 ± 2.17) % and absorbance value of β-carotene linoleic acid model at 180 min was (3.32 ± 1,12). H. atra extract were further fractionated, and ethyl acetate fractions (fr. 6) significantly inhibit radical activity at 180 min with the absorbance value of 2.84 ± 0.2. It can be concluded that H. atra is an important sea cucumber from tropical region.