A facile entry into a novel class of dispiroheterocycles through 1,3-dipolar cycloaddition

Abstract

The cycloaddition reaction of non-stabilized azomethine ylides, generated through decarboxylation and deprotonation, with (E)-2-arylidene-1-tetralones as dipolarophile has been investigated. A high degree of regioselectivity has been observed in the synthesis of a new class of functionalised dispiroheterocyclic compounds bearing a tetralone, acenapthenequinone and oxindole framework. © ARKAT.