The Effectiveness of Remdesivir versus Ruxolitinib as Covid-19 Supportive Management: Systematic Review, Meta-Analysis

Abstract

The treatment regimen in severe Covid-19 patients has several types of therapies. However, there is uncertainty about which therapies are more effective in the covid-19 weight category. In June 2020, the study was conducted with keyword search [REMDESIVIR] [RUXOLITINIB] [COVID19] in 2010-2020 using PUBMED.gov. This study used rct (randomization controller trial) method with the theme: the comparison of the effectiveness use of Remdesivir with Ruxolitinib on Covid-19. From the results of the analysis using forest plot obtained, there was a significant difference in the administration of Remdesivir therapy with Ruxolitinib on the improvement from covid-19 on day 7 (1.26 CI 95% 0.41 to 3.86) and day 14 (RR 1.26 CI 95% 0.41 to 3.86). Ruxolitinib therapy is more effective than Remdesivir applied for Covid-19 patients.