Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates

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Abstract

We report the microbiological characterization of four New Delhi metallo-β-lactamase-1 (blaNDM-1)-producing Enterobacteriaceae isolated in Rio de Janeiro, Brazil. blaNDM-1 was located on a conjugative plasmid and was associated with Klebsiella pneumoniae carbapenemase-2 (blaKPC-2) or aminoglycoside-resistance methylase (armA), a 16S rRNA methylase not previously reported in Brazil, in two distinct strains of Enterobacter cloacae. Our results suggested that the introduction of blaNDM-1 in Brazil has been accompanied by rapid spread, since our isolates showed no genetic relationship.

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Quiles, M. G., Rocchetti, T. T., Fehlberg, L. C., Kusano, E. J. U., Chebabo, A., Pereira, R. M. G., … Pignatari, A. C. C. (2015). Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates. Brazilian Journal of Medical and Biological Research, 48(2), 174–177. https://doi.org/10.1590/1414-431X20144154

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