Intra-ocular pressure and haemodynamic changes after tracheal intubation and extubation: A comparative study in glaucomatous and nonglaucomatous children

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Abstract

This prospective, controlled study was conducted to compare the effects of tracheal intubation and extubation on intra-ocular pressure changes and haemodynamic parameters in paediatric patients with and without glaucoma. The children were scheduled for intra-ocular surgery. Twenty children with normal intra-ocular pressure and 15 with glaucoma were studied. A standardised general anaesthetic was administered to both groups. After 5 min of anaesthesia, intra-ocular pressure, heart rate and noninvasive blood pressure were measured. These measurements were repeated 30 s and 2 min after tracheal intubation. Further measurements were taken before, and 30 s and 2 min after extubation. The increase in intra-ocular pressure after intubation was greater in the glaucomatous group than in the normal group. The increase in intra-ocular pressure was greater after extubation than intubation in both groups, but was similar in the two groups. However, because of the already increased intra-ocular pressure in glaucomatous children, they may be at an increased risk of visual damage after intubation and extubation.

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Madan, R., Tamilselvan, P., Sadhasivam, S., Shende, D., Gupta, V., & Kaul, H. L. (2000). Intra-ocular pressure and haemodynamic changes after tracheal intubation and extubation: A comparative study in glaucomatous and nonglaucomatous children. Anaesthesia, 55(4), 380–384. https://doi.org/10.1046/j.1365-2044.2000.01213.x

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