Diphencyprone has been reported as a local immunotherapy for cutaneous melanoma metastases. We aim to report cases of melanoma patients treated with diphencyprone in a single Brazilian institution and highlight their outcomes. Since 2012, we have treated 16 melanoma patients with cutaneous metastases with topical diphencyprone. To date, we have had 37.5% of complete response, 25% of partial responses, and 31.25% patients without any response. Treatment was well tolerated and local toxicity was easily controlled. We believe topical diphencyprone is a feasible treatment that can be another option for treating melanoma patients, especially in cases of in-transit or extensive disease.
CITATION STYLE
Gibbons, I. L., Bertolli, E., Pinto, C. A. L., Sonagli, M., de Macedo, M. P., & Neto, J. P. D. (2018). Diphencyprone as a therapeutic option in cutaneous metastasis of melanoma. A single-institution experience. Anais Brasileiros de Dermatologia, 93(2), 299–301. https://doi.org/10.1590/abd1806-4841.20187162
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