Analysis of cortical and mandibular trabeculae quality with β-crosslaps levels in postmenopausal women using cone-beam computed tomography

Abstract

Aim: This study aimed to assess the correlation between cortical and mandibular trabeculae quality with beta-crosslaps (β-CTx) levels in postmenopausal women. Materials and methods: This study analyzed both sites of cortical and trabecular mandibular below mental foramen obtained from 17 cone-beam computed tomography (CBCT) radiographs of postmenopausal women. The cortical parameters measured consisted of computed tomography index superior (CTI-S), computed tomography index inferior (CTI-I), and computed tomography mental index (CTMI); while the trabecular parameters consisted of bone volume fraction (BV/TV), trabecular thickness (Tb.Th), and trabecular space (Tb.Sp). The β-CTx level was examined, and then the results were correlated with the three parameters, each from both cortical and trabecular. Results: Both trabecular (r = 0.477; p = 0.049) and cortical (r = 0.411; p = 0.038) parameters had positive and significant correlations (p < 0.05) toward the β-CTx levels. Conclusion: Cone-beam computed tomography was able to assess cortical bone and mandibular trabeculae quality, which was correlated with the β-CTx level of postmenopausal women. Clinical significance: This study can be used as a consideration in detecting the decreased quality of the trabecular and cortical mandibular bone in postmenopausal women using CBCT and the β-CTx level before the severity occur.