Histopathology of the Skin

Abstract

Skin biopsy is the most frequently used and important test for dermatological diagnosis. In a biopsy, a sample of skin is collected for observation under the microscope. There are many cases in which it is impossible to make a diagnosis based only on the clinical symptoms. A blister, for example, may be caused by various pathomech- anisms, including viruses, bacteria and autoimmune diseases, or by heredity. It is often difficult to diagnose a blister just by naked-eye observation and disease history. To specify the cause of the disease and reach a final diagnosis, dermatopathological examination is essential.