Whole-genome sequencing of Burkholderia pseudomallei isolates from an unusual melioidosis case identifies a polyclonal infection with the same multilocus sequence type

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Abstract

Twelve Burkholderia pseudomallei isolates collected over a 32-month period from a patient with chronic melioidosis demonstrated identical multilocus sequence types (STs). However, whole-genome sequencing suggests a polyclonal infection. This study is the first to report a mixed infection with the same ST.

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Price, E. P., Sarovich, D. S., Viberg, L., Mayo, M., Kaestli, M., Tuanyok, A., … Currie, B. J. (2015). Whole-genome sequencing of Burkholderia pseudomallei isolates from an unusual melioidosis case identifies a polyclonal infection with the same multilocus sequence type. Journal of Clinical Microbiology, 53(1), 282–286. https://doi.org/10.1128/JCM.02560-14

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