Prevalence and relationship of hypertriglyceridaemic-waist phenotype and type 2 diabetes mellitus among a rural adult Chinese population

Abstract

Objective: Limited information is available on the prevalence and effect of hypertriglyceridaemic-waist (HTGW) phenotype on the risk of type 2 diabetes mellitus (T2DM) in rural populations. Design: In the present cross-sectional study, we investigated the prevalence of the HTGW phenotype and T2DM and the strength of their association among rural adults in China. Setting: HTGW was defined as TAG >1.7 mmol/l and waist circumference (WC) ≥90 cm for males and ≥80 cm for females. Logistic regression analysis yielded adjusted odds ratios (aOR) relating risk of T2DM with HTGW. Participants: Adults (n 12 345) aged 22.83-92.58 years were recruited from July to August of 2013 and July to August of 2014 from a rural area of Henan Province in China. Results: The prevalence of HTGW and T2DM was 23.71 % (males: 15.35 %; females: 28.88 %) and 11.79 % (males: 11.15 %; females: 12.18 %), respectively. After adjustment for sex, age, smoking, alcohol drinking, blood pressure, physical activity and diabetic family history, the risk of T2DM (aOR; 95 % CI) was increased with HTGW (v. normal TAG and WC: 3.23; CI 2.53, 4.13; males: 3.37; 2.30, 4.92; females: 3.41; 2.39, 4.85). The risk of T2DM with BMI≥28.0 kg/m 2 , simple enlarged WC and simple disorders of lipid metabolism showed an increasing tendency (aOR=1.31, 1.75 and 2.32). Conclusions: The prevalence of HTGW and T2DM has reached an alarming level among rural Chinese people, and HTGW is a significant risk factor for T2DM.