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Under arrest in mitosis: Cdc20 dies twice

Nature Cell Biology (2008) 10(12) 1385-1387
DOI: 10.1038/ncb1208-1385
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Abstract

The spindle assembly checkpoint is crucial for maintaining genome integrity in dividing cells by preventing premature chromosome segregation. Degradation of the APC/C activator Cdc20 seems to be an essential and conserved mechanism to maintain this checkpoint in the presence of chromosomes that are not attached to the mitotic spindle.

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APA

Fry, A. M., & Yamano, H. (2008). Under arrest in mitosis: Cdc20 dies twice. Nature Cell Biology, 10(12), 1385–1387. https://doi.org/10.1038/ncb1208-1385

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