Isoniazid inhibition of the synthesis of monosaturated long-chain fatty acids in Mycobacterium tuberculosis H37Ra

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Abstract

Ioniazid inhibited C24 and C26 monounsaturated fatty acid in M. tuberculosis H37Ra. Time courses of this inhibition and that of mycolic acid synthesis were similar.

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Davidson, L. A., & Takayama, K. (1979). Isoniazid inhibition of the synthesis of monosaturated long-chain fatty acids in Mycobacterium tuberculosis H37Ra. Antimicrobial Agents and Chemotherapy, 16(1), 104–105. https://doi.org/10.1128/AAC.16.1.104

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