Synthesis of novel, potentially biologically active dibenzosuberone derivatives

Abstract

Novel representatives of the important group of biologically active dibenzosuberone derivatives were prepared: 3,7-dibromo-5- (dimethylaminoethyloxyimino)-10,11-dihydro-5H-dibenzo[a,d]cyclohepta-1,4-diene (1), 3,7-dibromo-5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d] cycloheptene (2) and 1,7-dibromo-5-(3-dimethylaminopropylidene)-10,11-dihydro- 5H-dibenzo-[a,d]-cycloheptene (3). These compounds are potential tricyclic antidepressants (TCAs), which are still the most frequently prescribed antidepressants in many countries. © 2005 by MDPI.