Journal Article

An unprecedented case of dodecamorphism: The twelfth polymorph of aripiprazole formed by seeding with its active metabolite

CrystEngComm (2016) 18(9) 1486-1488
DOI: 10.1039/c5ce02467f
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Abstract

A new polymorph of aripiprazole has been discovered, making it the most polymorphic drug to date with twelve reported anhydrous forms, and a record-breaking ninth solved crystal structure. The new form was induced by seeding with crystals of the active metabolite dehydro-aripiprazole.

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APA

Zeidan, T. A., Trotta, J. T., Tilak, P. A., Oliveira, M. A., Chiarella, R. A., Foxman, B. M., … Hickey, M. B. (2016). An unprecedented case of dodecamorphism: The twelfth polymorph of aripiprazole formed by seeding with its active metabolite. CrystEngComm, 18(9), 1486–1488. https://doi.org/10.1039/c5ce02467f

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