Self-organization and shape change by active polarization in nematic droplets

Abstract

Active forces drive critical biological processes such as spontaneous organization and shape change during cell division. Here, we present a minimal hydrodynamic model leading to a unified description of self-organization and division in nematic droplets through active polarity sorting of cytoskeletal filaments by molecular motors. We find that motors self-organize within droplets while structuring filaments into polarized aster defects. At large activity, motors deform droplets leading to multidroplet chains and droplet division, consistent with experiments on actomyosin tactoids. We predict droplet steady-state phase diagrams that inform programmable shape changes in confined soft materials.