Drug-Induced Acneiform Eruptions

Abstract

Acne vulgaris is a polymorphic infl ammatory skin disease, clinically characterized by mixture of comedones, superficial and deep infl amed papules, pustules, and nodules. It is a chronic infl ammation of the pilosebaceous unit. Acneiform drug eruptions are a monomorphic infl ammatory skin disease lacking comedones with lesions typically in the same stage. This type of drug eruption has an abrupt onset and is often associated with various medications (Table 54.1). The pathogenesis of acneiform drug eruptions is poorly understood; documented evidence when available will be presented under the specific drug categories in this chapter.