Enzyme models and organometallic chemistry

Abstract

This lecture deals with some of the activities within our group in recent years in the areas of macrocycles, thiacrown ethers, and amino acids as ligands. Macrocycles activated by a metal are used as mimics of some aspects of alcohol dehydrogenase. Metal complexes of thiacrown ethers are employed in catalytic enantioselective synthesis of carbon-carbon bonds. Aminophosphines derived from natural and unnatural amino acids are employed as ligands for nickel and palladium in catalytic enantioselective synthesis. © 1992 IUPAC