Importance of early and multidisciplinary intervention in patients with coexistent juvenile idiopathic arthritis and familial mediterranean fever

Abstract

Familial Mediterranean fever (FMF) and juvenile idiopathic arthritis (JIA) are childhood-associated diseases that are rarely found to coexist. Treatment includes non-steroidal anti-inflammatory drugs (NSAIDs), intra-articular steroid injections, immunosuppressants, increased range of motion and strength, and prevention and correction of deformities that require a multidisciplinary approach. Here, we describe the clinical presentation, radiological findings, and management strategies of a 19-year-old male with a diagnosis of JIA and FMF presenting with musculoskeletal deformities. Coexistence of JIA and FMF has a progressive nature and can result in severe joint erosions, development of joint contractures, muscle atrophy, and osteoporosis, despite medical treatment. A multidisciplinary approach including an early and intensive rehabilitation program with regular follow-up can be considered as an important adjunct to medical treatment. This in turn may reduce disability and improve quality of life.