The premenstrual tension syndrome and its treatment

Abstract

The clinical features of premenstrual tension are described and the possible mode of origin of the various symptoms is discussed. Hydration, blood chemistry changes, autonomic nervous system responses, as well as psychogenic and personality factors are believed to play a part in the syndrome. A working hypothesis on which treatment was based is postulated. Treatment was applied at various aetiological levels, including psychotherapy, dehydration therapy, and administration of progestogens and androgens. Psychotherapy has an important but limited role. Dehydration therapy was found to alleviate some of the symptoms only. The most effective methods of treatment were administration of a progestogen such as ethisterone or an androgen such as methyltestosterone during the second half of the menstrual cycle. © 1953, British Medical Journal Publishing Group. All rights reserved.