Adult Human Glioblastomas Harbor Radial Glia-like Cells

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Abstract

Tabar and colleagues report that adult brain tumors comprise neoplastic radial glia-like cells reminiscent of normal radial glia of early development. They are responsive to inflammation signals and may represent putative stem cells of origin of this lethal tumor.

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Wang, R., Sharma, R., Shen, X., Laughney, A. M., Funato, K., Clark, P. J., … Tabar, V. (2020). Adult Human Glioblastomas Harbor Radial Glia-like Cells. Stem Cell Reports, 14(2), 338–350. https://doi.org/10.1016/j.stemcr.2020.01.007

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