The innate function of circular RNAs

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Abstract

Duplex-forming circular RNAs interact with PKR and repress aberrant activation of innate immunity. Upon viral infection, PKR is activated through the degradation of these circular RNAs by RNase L.

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Zlotorynski, E. (2019, July 1). The innate function of circular RNAs. Nature Reviews Molecular Cell Biology. Nature Publishing Group. https://doi.org/10.1038/s41580-019-0146-y

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