Abstract
Background: Relationship of autophagosomes with endosomal vesicles varies in different conditions. Results: Calcium phosphate precipitates required endocytosis to induce autophagy, caused endosome damage, and recruited autophagosomes to the damaged vesicles. Conclusion: Damaged endosomes can be targeted by autophagosomes. Significance: Autophagy may play a role in endosomal homeostasis. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.
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CITATION STYLE
Chen, X., Khambu, B., Zhang, H., Gao, W., Li, M., Chen, X., … Yin, X. M. (2014). Autophagy induced by calcium phosphate precipitates targets damaged endosomes. Journal of Biological Chemistry, 289(16), 11162–11174. https://doi.org/10.1074/jbc.M113.531855
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