DynaBioS: A platform for cell/biodynamics simulators

Abstract

Biological simulation has become an important technology for biological research. Though multi-domain simulation technique is required for analysis of complicated biological activities, multi-domain biosimuator system tends to be very complicated and so requires a high developing cost. To improve this situation, we propose a biosimulator development platform, DynaBioS, which can handle complex interactions between phenomena in different domains, such as electrophysiology and mechanics. A biosimulator system is composed of components, each of which is a sub-simulator of a phenomenon, and exchanges event messages to each others as the interaction of the phenomena. This design allows easy replacement of a model for a phenomena by interchanging a corresponding component. This platform reduces costs to develop simulators, by implementation of components by wrapping existing software products, and by reuse of components. Examples of developed simulators are given to show that this platform facilitates the development of biosimulators.