Epidemiologic survey and analysis of mild cognitive impairment amongst community senior citizens of Changsha City

Abstract

ObjectiveThe purpose of the current study was to conduct a mild cognitive impairment (MCI) prevalence survey among the community senior citizens of Changsha City and analyze possible relevant factors so as to perform early screening and intervention for MCI patients, and delay or prevent MCI from developing into Alzheimer’s disease (AD).MethodsBetween April and September 2012, a total of 1764 community senior citizens in Changsha City were selected through multi-stage and random cluster sampling as study subjects. The following tables were used during the investigation to perform preliminary MCI screening for the subjects of this study: a general information survey; Mini-Mental State Examination (MMSE); Montreal Cognitive Assessment (MoCA); Beijing version; Global Deteriorate Scale (GDS); Clinical Dementia Rating (CDR) scale; and Activities of Daily Living (ADL) scale. Then, neurology specialists made diagnoses according to the actual status of subjects, survey findings, and clinical MCI diagnostic standards. The prevalence of MCI was calculated and the rates concerning senior citizens with different demographic characteristics were compared. Logistic regression analysis was used to analyze relevant factors that led to MCI, and comparing findings with those of other cities was conducted.ResultsThe MCI prevalence among senior citizens in Changsha City was 16.27% (287/1 764). The MCI prevalence increased with age [for the 60, 70, and 80 age groups, the prevalence was 9.79% (84/858), 20.14% (149/740), and 32.53% (54/166), respectively, P0.05), but lower than Shanghai [35.78% (161/450)] and higher than Chengdu [2.35% (92/3 910)] (P<0.05).ConclusionThe prevalence of MCI among the community senior citizens of Changsha City is highly related to factors like age, educational background, and marital status. Prevention against these high-risk factors shall be carried out to delay cognitive decline for senior citizens.